BIOPEP-UWM: Report

ID 11052
Name Acetylcholinesterase inhibitor
sequence
QWPAQ

Function:
Antioxidative
 
Number of residues
5
Activity code
ache
Activity :
AChE inhibitor
Chemical mass 628.6751 Monoisotopic mass 628.2960
IC50 :
22.29 µM



Bibliographic data:
Authors
Li Y., Gao S., Zhang X., Cao Z., Guo Y., Zhao R., Li L., Liu Y., Qin Q., Yi B., Zhao G.
Title
Efficient screening of synergistic antioxidant and AChE inhibitory peptides from sea cucumber (Stichopus japonicus) using a novel approach combining de novo sequencing and parallel peptide synthesis. Peptide Sci., 117, e70002, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O

InChI=1S/C29H40N8O8/c1-15(25(40)35-20(29(44)45)9-11-24(32)39)34-27(42)22-7-4-12-37(22)28(43)21(36-26(41)18(30)8-10-23(31)38)13-16-14-33-19-6-3-2-5-17(16)19/h2-3,5-6,14-15,18,20-22,33H,4,7-13,30H2,1H3,(H2,31,38)(H2,32,39)(H,34,42)(H,35,40)(H,36,41)(H,44,45)/t15-,18-,20-,21-,22-/m0/s1

InChIKey=MVVPGQZIGPOUSU-NHWIGJJZSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides



Database reference: