BIOPEP-UWM: Report

ID 11068
Name Acetylcholinesterase inhibitor
sequence
YPGQLT

Function:
Inhibitor of acetylcholinestrase (EC 3.1.1.7)
 
Number of residues
6
Activity code
ache
Activity :
AChE inhibitor
Chemical mass 677.7439 Monoisotopic mass 677.3373
IC50 :
6.76 µM



Bibliographic data:
Authors
Li Y., Gao S., Zhang X., Cao Z., Guo Y., Zhao R., Liu Y., Li X., Lin H., Qin Q., Yi B., Zhao G.
Title
Joint technique “parallel peptide synthesis & de novo sequencing” development for the structure verification and high-throughput activity screening of biological peptides from sea cucumber (Stichopus japonicus) intestinal hydrolysate. Food Res. Int., 212, 116475, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H](CC1=CC=C(C=C1)O)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)O

InChI=1S/C31H47N7O10/c1-16(2)13-22(28(44)37-26(17(3)39)31(47)48)36-27(43)21(10-11-24(33)41)35-25(42)15-34-29(45)23-5-4-12-38(23)30(46)20(32)14-18-6-8-19(40)9-7-18/h6-9,16-17,20-23,26,39-40H,4-5,10-15,32H2,1-3H3,(H2,33,41)(H,34,45)(H,35,42)(H,36,43)(H,37,44)(H,47,48)/t17-,20+,21+,22+,23+,26+/m1/s1

InChIKey=MFWBIHSHUOCHOK-IVYQXGQGSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides




Database reference: