BIOPEP-UWM: Report

ID 11074
Name Acetylcholinesterase inhibitor
sequence
LFADP

Function:
Inhibitor of acetylcholinestrase (EC 3.1.1.7)
 
Number of residues
5
Activity code
ache
Activity :
AChE inhibitor
Chemical mass 561.6257 Monoisotopic mass 561.2789
IC50 :
174.60 µM



Bibliographic data:
Authors
Li Y., Gao S., Zhang X., Cao Z., Guo Y., Zhao R., Liu Y., Li X., Lin H., Qin Q., Yi B., Zhao G.
Title
Joint technique “parallel peptide synthesis & de novo sequencing” development for the structure verification and high-throughput activity screening of biological peptides from sea cucumber (Stichopus japonicus) intestinal hydrolysate. Food Res. Int., 212, 116475, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C27H39N5O8/c1-15(2)12-18(28)24(36)30-19(13-17-8-5-4-6-9-17)25(37)29-16(3)23(35)31-20(14-22(33)34)26(38)32-11-7-10-21(32)27(39)40/h4-6,8-9,15-16,18-21H,7,10-14,28H2,1-3H3,(H,29,37)(H,30,36)(H,31,35)(H,33,34)(H,39,40)/t16-,18-,19-,20-,21-/m0/s1

InChIKey=FOYUVCYBKQDJFB-MQBSTWLZSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides




Database reference: