BIOPEP-UWM: Report

ID 11100
Name Antiartherosclerotic peptide
sequence
WH
Function:
Antiartherosclerotic
 
Number of residues
2
Activity code
aart
Activity :
antiartherosclerotic
Chemical mass 341.3637 Monoisotopic mass 341.1484
IC50 :
17.03 µM


Bibliographic data:
Authors
Matsui T., Sato M., Tanaka M., Yamada Y., Watanabe S., Fujimoto Y., Imaizumi K., Matsumoto K.
Title
Vasodilating dipeptide Trp-His can prevent artherosclerosis in apo-E deficient mice. Brit. J. Nutr., 103, 309-313, 2010
Year Source
2010 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)O

InChI=1S/C17H19N5O3/c18-13(5-10-7-20-14-4-2-1-3-12(10)14)16(23)22-15(17(24)25)6-11-8-19-9-21-11/h1-4,7-9,13,15,20H,5-6,18H2,(H,19,21)(H,22,23)(H,24,25)/t13-,15-/m0/s1

InChIKey= KBUBZAMBIVEFEI-ZFWWWQNUSA-N


Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 10294)
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8931)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the EROP-Moscow database


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8931; 19294

BRENDA: Ligand L-tryptophyl-L-histidine

ChEBI: ID 157899

DFBP: ID DFBPDPIV0168

EROP-Moscow ID E10437

J-GLOBAL: ID 200907084427481793

Metabolomics Workbench: ID 79004

Nikkaji: ID J2.719.890B

PubChem: CID 10154381

SureChEMBL: ID SCHEMBL21641790

UniChem: ID 25738600

Wikidata: ID Q106026519

ZINC: ID ZINC000034334192