BIOPEP-UWM: Report

ID 11101
Name Anxiolytic peptide
sequence
FL

Function:
Anxiolytic-like activity in mice
 
Number of residues
2
Activity code
ne
Activity :
neuropeptide
Chemical mass 278.3459 Monoisotopic mass 278.1625
EC50 :
0.00 µM



Bibliographic data:
Authors
Mizushige T., Kanegawa N., Yamada A., Ota A., Kanamoto R., Ohinata K.
Title
Aromatic amino acid-leucine dipeptides exhibit anxiolytic-like activity in young mice. Neurosci. Lett., 543, 126-129, 2013
Year Source
2013 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])(CC(C)C)C(=O)O

InChI=1S/C15H22N2O3/c1-10(2)8-13(15(19)20)17-14(18)12(16)9-11-6-4-3-5-7-11/h3-7,10,12-13H,8-9,16H2,1-2H3,(H,17,18)(H,19,20)/t12-,13-/m0/s1

InChIKey=RFCVXVPWSPOMFJ-STQMWFEESA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BindingDB database; the BRENDA database; the EROP-Moscow database; the PubChem database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to BIOPEP-UWM database of bioactive peptides; the EROP-Moscow database
Inhibitor of pseudolysin (EC 3.4.24.26) (MEROPS ID: M04.005) according to the BRENDA database
Inhibitor of Aminopeptidase B (EC 3.4.11.6) (MEROPS ID: M01.014) according to the BindingDB database; the ChEMBL database
Inhibitor of Membrane alanyl aminopeptidase (EC 3.4.11.2) (MEROPS ID: M01.001 (another names: aminopeptidase M; aminopeptidase N) according to the BindingDB database; the ChEMBL database
Inhibitor of Neprilysin (EC 3.4.24.11) (MEROPS ID: M13.001) according to the BindingDB database; the ChEMBL database
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9505)

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 42); the BitterDB database; the ChEMBL database; the PubChem database



Database reference:
ACToR: ID 3303-55-7

AHTPDB: ID 1219; 1436; 1988; 3877; 5411; 5415

BindingDB: ID 50282727

BioPepDB: ID biopep00251

BIOPEP-UWM database of bioactive peptides: ID 8555

BIOPEP-UWM database of sensory peptides and amino acids: ID 42

BitterDB: ID 836

BRENDA: Ligand Phe-Leu

CAS: Registry No 3303-55-7

ChEBI: ID 91150

ChEMBL: ID CHEMBL37879

ChemIDplus: ID 3303-55-7

ChemSpider ID: 69264

CTD: ID 3303-55-7

DFBP: ID DFBPACEI0246; DFBPANOX0759; DFBPDPIV0177; DFBPMUFU0081

EPA CompTox: ID DTXSID60954651

EROP-Moscow: ID E01597

J-GLOBAL: ID 200907070370465370

MBPDB: Peptide FL

Metabolights: ID MTBLC91150

Metabolomics Workbench: ID 78926

Nikkaji: ID J80.688I

PubChem: CID 76808

SATPdb: ID satpdb22674

SureChEMBL: ID SCHEMBL1396480

Wikidata: ID Q27163086

ZINC: ID ZINC000002390944