BIOPEP-UWM: Report

ID 11102
Name Anxiolytic peptide
sequence
WL
Function:
Anxiolytic-like activity in mice
 
Number of residues
2
Activity code
ne
Activity :
neuropeptide
Chemical mass 317.3819 Monoisotopic mass 317.1734
EC50 :
0.00 µM


Bibliographic data:
Authors
Mizushige T., Kanegawa N., Yamada A., Ota A., Kanamoto R., Ohinata K.
Title
Aromatic amino acid-leucine dipeptides exhibit anxiolytic-like activity in young mice. Neurosci. Lett., 543, 126-129, 2013
Year Source
2013 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC(C)C[C@H](NC(=O)[C@@H](N)CC1=CNC2=CC=CC=C12)C(O)=O

InChI=1S/C17H23N3O3/c1-10(2)7-15(17(22)23)20-16(21)13(18)8-11-9-19-14-6-4-3-5-12(11)14/h3-6,9-10,13,15,19H,7-8,18H2,1-2H3,(H,20,21)(H,22,23)/t13-,15-/m0/s1

InChIKey=LYMVXFSTACVOLP-ZFWWWQNUSA-N


Inhibitor of Peroxisome proliferator-activated receptor gamma according to BindingDB database; ChEMBL database
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8677)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BIOPEP-UWM database of bioactive peptides (ID 9107); the BRENDA database; the DFBP database; the EROP-Moscow database
Immunomodulating peptide according to the DFBP database

Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 338); the BitterDB database


Database reference:
AHTPDB: ID 1463; 1900; 2968; 4724; 5181; 6216; 6220; 6862

BindingDB: ID 50266681

BIOPEP-UWM database of bioactive peptides: ID 8677; 9107

BIOPEP-UWM database of sensory peptides and amino acids: ID 338

BRENDA: Ligand Trp-Leu

BitterDB: ID 830

ChEBI: ID 74871

ChEMBL: ID CHEMBL477627

ChemSpider: ID 5365198

DFBP: ID DFBPANOX0077; DFBPIMMU0024; DFBPMUFU0213

EROP-Moscow: ID E06385

FooDB: ID DB098230

HMDB: ID HMDB0029087

J-GLOBAL: ID 200907089186452560

MeSH: Terms Trp-Leu; tryptophan-leucine

Metabolights: ID MTBLC74871

Metabolomics Workbench: ID 79006

Nikkaji: ID J236.159K

PubChem: ID 6997509

SATPdb: ID satpdb20928

SureChEMBL: ID SCHEMBL7622341

Therapeutic Target Database (TTD): ID DNC009657

UniChem: ID 299509

Wikidata: ID Q27144982

ZINC: ID ZINC000001865984