BIOPEP-UWM: Report

ID 11107
Name ACE inhibitor
sequence
IVGFPAYGH

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
10
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 960.0835 Monoisotopic mass 959.4850
IC50 :
150.88 µM



Bibliographic data:
Authors
Zou L., Zhou Y., Yu X., Chen C., Xiao G.
Title
Angiotensin I-converting enzyme inhibitory activity of two peptides derived from in vitro digestion Products of pork sausage with partial substitution of NaCl by KCl. J. Agric. Food Chem., 71, 10638–10646, 2023
Year Source
2023 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)NCC(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)O

InChI=1S/C47H65N11O11/c1-6-27(4)39(48)44(65)57-40(26(2)3)45(66)51-24-37(60)54-34(20-29-11-8-7-9-12-29)46(67)58-18-10-13-36(58)43(64)53-28(5)41(62)56-33(19-30-14-16-32(59)17-15-30)42(63)50-23-38(61)55-35(47(68)69)21-31-22-49-25-52-31/h7-9,11-12,14-17,22,25-28,33-36,39-40,59H,6,10,13,18-21,23-24,48H2,1-5H3,(H,49,52)(H,50,63)(H,51,66)(H,53,64)(H,54,60)(H,55,61)(H,56,62)(H,57,65)(H,68,69)/t27-,28-,33-,34-,35-,36-,39-,40-/m0/s1

InChIKey=HORDNDFEIYCFTQ-YXCWFEPDSA-N



Database reference: