BIOPEP-UWM: Report

ID 11114
Name ACE inhibitor
sequence
YI
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 294.3453 Monoisotopic mass 294.1574
IC50 :
316.00 µM


Bibliographic data:
Authors
Foltz M., van Buren L., Klaffke W., Duchateau G. S. M. J. E.
Title
Modeling of the relationship between dipeptide structure and dipeptide stability permeability and ACE inhibitory activity. J. Food Sci., 74, H234-H251, 2009
Year Source
2009 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)O

InChI=1S/C15H22N2O4/c1-3-9(2)13(15(20)21)17-14(19)12(16)8-10-4-6-11(18)7-5-10/h4-7,9,12-13,18H,3,8,16H2,1-2H3,(H,17,19)(H,20,21)/t9-,12-,13-/m0/s1

InChIKey=QJKMCQRFHJRIPU-XDTLVQLUSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8938); the BRENDA database
Antinociceptive peptide according to the BIOPEP-UWM database of bioactive peptides; the ChEMBL database
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9510)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8938, 9510

BRENDA: Ligand L-Tyr-L-Ile

ChEBI: ID 74993

ChEMBL: ID CHEMBL299835

ChemSpider: ID 5382077

EROP-Moscow: ID E10360

FooDB: ID FDB112112

HMDB: ID HMDB0029108

J-GLOBAL: ID 200907081806717444

Metabolights: ID MTBLC74993

Metabolomics Workbench: ID 79025

Nikkaji: J535.352A

PubChem: CID 7019109

SureChEMBL: ID SCHEMBL9822685

Wikidata: ID Q27145058

ZINC: ID ZINC000002556667