BIOPEP-UWM: Report

ID 11115
Name Antinociceptive peptide
sequence
YI
Function:
Antinociceptive
 
Number of residues
2
Activity code
ne
Activity :
neuropeptide
Chemical mass 294.3453 Monoisotopic mass 294.1574
EC50 :
0.00 µM


Bibliographic data:
Authors
Cain G. A., Christos T. E., Johnson A L., Pottorf R. S., Tam S. W., Schmidt W. K.
Title
Identification of simpler analogs of neurotensin (9-13) which retain antinociceptive activity. Bioorg. Med. Chem. Lett., 3, 1767-1772, 1993
Year Source
1993 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)O

InChI=1S/C15H22N2O4/c1-3-9(2)13(15(20)21)17-14(19)12(16)8-10-4-6-11(18)7-5-10/h4-7,9,12-13,18H,3,8,16H2,1-2H3,(H,17,19)(H,20,21)/t9-,12-,13-/m0/s1

InChIKey=QJKMCQRFHJRIPU-XDTLVQLUSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8938); the BRENDA database
Inhibitor of Dipeptidyl peptidase-III (DPP-III) (EC 3.4.14.4) (MEROPS ID: M49.001) according to the BIOPEP-UWM database of bioactive peptides (ID 9510)
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides; the EROP-Moscow database


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8938, 9510

BRENDA: Ligand L-Tyr-L-Ile

ChEBI: ID 74993

ChEMBL: ID CHEMBL299835

ChemSpider: ID 5382077

EROP-Moscow: ID E10360

FooDB: ID FDB112112

HMDB: ID HMDB0029108

J-GLOBAL: ID 200907081806717444

Metabolights: ID MTBLC74993

Metabolomics Workbench: ID 79025

Nikkaji: J535.352A

PubChem: CID 7019109

SureChEMBL: ID SCHEMBL9822685

Wikidata: ID Q27145058

ZINC: ID ZINC000002556667