BIOPEP-UWM: Report

ID 11143
Name ACE inhibitor
sequence
PVEPFTESQ

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
9
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1033.0862 Monoisotopic mass 1032.4747
IC50 :
1.57 µM



Bibliographic data:
Authors
Magouz O., Ibrahim M. A. A., Mehanna N., Gensberger-Reigl S., Dalabasmaz S., Pischetsrieder M.
Title
Identification of the heptapeptide PR7 and octapeptide SF8 with potent antioxidative and angiotensin converting enzyme inhibitory activity from the fermented dairy by-product “Buttermilk". Food Front., 6, 837–851, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O

InChI=1S/C46H68N10O17/c1-23(2)36(54-38(64)26-11-7-19-48-26)43(69)50-28(15-18-35(62)63)45(71)56-20-8-12-32(56)42(68)52-30(21-25-9-5-4-6-10-25)40(66)55-37(24(3)58)44(70)49-27(14-17-34(60)61)39(65)53-31(22-57)41(67)51-29(46(72)73)13-16-33(47)59/h4-6,9-10,23-24,26-32,36-37,48,57-58H,7-8,11-22H2,1-3H3,(H2,47,59)(H,49,70)(H,50,69)(H,51,67)(H,52,68)(H,53,65)(H,54,64)(H,55,66)(H,60,61)(H,62,63)(H,72,73)/t24-,26+,27+,28+,29+,30+,31+,32+,36+,37+/m1/s1

InChIKey=QKVQFNSZBSARRA-OBALASBNSA-N





Database reference: