BIOPEP-UWM: Report

ID 11146
Name ACE inhibitor
sequence
VAPFPEV

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
8
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 757.8713 Monoisotopic mass 757.3997
IC50 :
0.00 µM



Bibliographic data:
Authors
Magouz O., Ibrahim M. A. A., Mehanna N., Gensberger-Reigl S., Dalabasmaz S., Pischetsrieder M.
Title
Identification of the heptapeptide PR7 and octapeptide SF8 with potent antioxidative and angiotensin converting enzyme inhibitory activity from the fermented dairy by-product “Buttermilk". Food Front., 6, 837–851, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)O

InChI=1S/C37H55N7O10/c1-20(2)29(38)34(50)39-22(5)35(51)43-17-9-13-26(43)33(49)41-25(19-23-11-7-6-8-12-23)36(52)44-18-10-14-27(44)32(48)40-24(15-16-28(45)46)31(47)42-30(21(3)4)37(53)54/h6-8,11-12,20-22,24-27,29-30H,9-10,13-19,38H2,1-5H3,(H,39,50)(H,40,48)(H,41,49)(H,42,47)(H,45,46)(H,53,54)/t22-,24-,25-,26-,27-,29-,30-/m0/s1

InChIKey=NKBNJBMJISHPIG-KNWHVVHCSA-N



Database reference: