BIOPEP-UWM: Report

ID 11149
Name ACE inhibitor
sequence
PFPGPIH

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 763.8808 Monoisotopic mass 763.4005
IC50 :
0.00 µM



Bibliographic data:
Authors
Magouz O., Ibrahim M. A. A., Mehanna N., Gensberger-Reigl S., Dalabasmaz S., Pischetsrieder M.
Title
Identification of the heptapeptide PR7 and octapeptide SF8 with potent antioxidative and angiotensin converting enzyme inhibitory activity from the fermented dairy by-product “Buttermilk". Food Front., 6, 837–851, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)O

InChI=1S/C38H53N9O8/c1-3-23(2)32(36(52)44-28(38(54)55)19-25-20-39-22-42-25)45-35(51)30-14-8-16-46(30)31(48)21-41-34(50)29-13-9-17-47(29)37(53)27(18-24-10-5-4-6-11-24)43-33(49)26-12-7-15-40-26/h4-6,10-11,20,22-23,26-30,32,40H,3,7-9,12-19,21H2,1-2H3,(H,39,42)(H,41,50)(H,43,49)(H,44,52)(H,45,51)(H,54,55)/t23-,26-,27-,28-,29-,30-,32-/m0/s1

InChIKey=WEOSVMCYWHAVQF-APYWWOEASA-N






Database reference: