BIOPEP-UWM: Report

ID 11150
Name ACE inhibitor
sequence
PQNIPPLTQT
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
11
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1108.2417 Monoisotopic mass 1107.5905
IC50 :
0.00 µM


Bibliographic data:
Authors
Magouz O., Ibrahim M. A. A., Mehanna N., Gensberger-Reigl S., Dalabasmaz S., Pischetsrieder M.
Title
Identification of the heptapeptide PR7 and octapeptide SF8 with potent antioxidative and angiotensin converting enzyme inhibitory activity from the fermented dairy by-product “Buttermilk". Food Front., 6, 837–851, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)O

InChI=1S/C49H81N13O16/c1-7-24(4)37(58-44(72)31(22-36(52)67)56-41(69)28(14-16-34(50)65)54-40(68)27-11-8-18-53-27)48(76)62-20-10-13-33(62)47(75)61-19-9-12-32(61)45(73)57-30(21-23(2)3)43(71)59-38(25(5)63)46(74)55-29(15-17-35(51)66)42(70)60-39(26(6)64)49(77)78/h23-33,37-39,53,63-64H,7-22H2,1-6H3,(H2,50,65)(H2,51,66)(H2,52,67)(H,54,68)(H,55,74)(H,56,69)(H,57,73)(H,58,72)(H,59,71)(H,60,70)(H,77,78)/t24-,25+,26+,27-,28-,29-,30-,31-,32-,33-,37-,38-,39-/m0/s1

InChIKey=MWRRJEUXCOHNHI-FWINVJERSA-N


Database reference: