BIOPEP-UWM: Report

ID 11151
Name ACE inhibitor
sequence
PVLGPVRGPF

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
11
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1038.2396 Monoisotopic mass 1037.6004
IC50 :
0.00 µM



Bibliographic data:
Authors
Magouz O., Ibrahim M. A. A., Mehanna N., Gensberger-Reigl S., Dalabasmaz S., Pischetsrieder M.
Title
Identification of the heptapeptide PR7 and octapeptide SF8 with potent antioxidative and angiotensin converting enzyme inhibitory activity from the fermented dairy by-product “Buttermilk". Food Front., 6, 837–851, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C50H79N13O11/c1-28(2)24-34(58-48(72)40(29(3)4)60-44(68)32-16-10-20-53-32)43(67)56-27-39(65)63-23-13-19-37(63)46(70)61-41(30(5)6)47(71)57-33(17-11-21-54-50(51)52)42(66)55-26-38(64)62-22-12-18-36(62)45(69)59-35(49(73)74)25-31-14-8-7-9-15-31/h7-9,14-15,28-30,32-37,40-41,53H,10-13,16-27H2,1-6H3,(H,55,66)(H,56,67)(H,57,71)(H,58,72)(H,59,69)(H,60,68)(H,61,70)(H,73,74)(H4,51,52,54)/t32-,33-,34-,35-,36-,37-,40-,41-/m0/s1

InChIKey=UTXZIRKGCIZCKP-LWKWHTFQSA-N







Database reference: