BIOPEP-UWM: Report

ID 11157
Name ACE inhibitor
sequence
TPLPLAGPPR

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
10
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 1018.2069 Monoisotopic mass 1017.5953
IC50 :
1.57 µM



Bibliographic data:
Authors
Magouz O., Ibrahim M. A. A., Mehanna N., Gensberger-Reigl S., Dalabasmaz S., Pischetsrieder M.
Title
Identification of the heptapeptide PR7 and octapeptide SF8 with potent antioxidative and angiotensin converting enzyme inhibitory activity from the fermented dairy by-product “Buttermilk". Food Front., 6, 837–851, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(O)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C47H79N13O12/c1-25(2)22-30(55-41(66)32-13-8-19-58(32)43(68)31(23-26(3)4)56-42(67)34-15-10-21-60(34)45(70)37(48)28(6)61)39(64)53-27(5)38(63)52-24-36(62)57-18-11-16-35(57)44(69)59-20-9-14-33(59)40(65)54-29(46(71)72)12-7-17-51-47(49)50/h25-35,37,61H,7-24,48H2,1-6H3,(H,52,63)(H,53,64)(H,54,65)(H,55,66)(H,56,67)(H,71,72)(H4,49,50,51)/t27-,28+,29-,30-,31-,32-,33-,34-,35-,37-/m0/s1

InChIKey=MFEUJIZMZQSPBD-DMBNOETDSA-N








Database reference: