BIOPEP-UWM: Report

ID 11192
Name Hypotensive peptide
sequence
IW
Function:
Lowering blood pressure in rats
 
Number of residues
2
Activity code
hyp
Activity :
hypotensive
Chemical mass 317.3819 Monoisotopic mass 317.1734
EC50 :
0.00 µM


Bibliographic data:
Authors
Sato M., Hosokawa T., Yamaguchi T., Nakano T., Muramoto K., Kahara T., Funayama K., Kobayashi A., Nakano T.
Title
Angiotensin I-converting enzyme inhibitory peptides derived from wakame (Undaria pinnatifida) and their antihypertensive effect in spontaneously hypertensive rats. J. Agric. Food Chem., 50, 6245-6252, 2002
Year Source
2002 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: CC[C@H](C)[C@H](N)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(O)=O

InChI=1S/C17H23N3O3/c1-3-10(2)15(18)16(21)20-14(17(22)23)8-11-9-19-13-7-5-4-6-12(11)13/h4-7,9-10,14-15,19H,3,8,18H2,1-2H3,(H,20,21)(H,22,23)/t10-,14-,15-/m0/s1

InChIKey=BVRPESWOSNFUCJ-LKTVYLICSA-N


Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database; the BindingDB database; the BIOPEP-UWM database of bioactive peptides (ID 7544); the ChEMBL database; the EROP-Moscow database; the SATPdb database
Inhibitor of Xanthine oxidase (EC 1.17.3.2) according to the EROP-Moscow database
Neuropeptide BNC210 according to the ChemSpider database; the EROP-Moscow database; the Wikipedia
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) accprding to the BIOPEP-UWM database of bioactive peptides (ID 8807)


Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids; the ChEMBL database


Database reference:
AHTPDB: ID 1074; 1085; 1444; 1460; 1468; 1859; 2028; 2214; 2779; 2788; 2847; 2882; 3343; 3503; 3567; 3780; 3863; 3961; 4227; 4237; 4255; 4451; 4486; 4649; 4958; 4959; 5155; 6160; 6264; 6272; 6531; 6880

BindingDB: ID 50407421

BioPepDB: ID biopep00616

BIOPEP-UWM database of bioactive peptides: ID 7544; 8807

BIOPEP-UWM database of sensory peptides and amino acids: ID 346

ChEBI: ID 74080

ChEMBL: ID CHEMBL56923

ChemSpider: ID 5382052

DFBP: ID DFBPACEI1173, DFBPANHY0619, DFBPANHY0920, DFBPINPE0019, DFBPMUFU0232

EROP-Moscow: ID E01434

J-GLOBAL: ID 200907081268045678

Metabolights: ID MTBLC74080

Nikkaji: ID J587.917E

OLSVis: ID CHEBI:74080

PubChem: ID 7019084

SATPdb: ID satpdb20183

ZINC: ID ZINC02556614