BIOPEP-UWM: Report

ID 11202
Name PPARγ antagonist
sequence
we
Function:
Antagonist of Peroxisome proliferator-activated receptor γ (PPARγ)
 
Number of residues
2
Activity code
ppar
Activity :
PPARγ antagonist
Chemical mass 333.3384 Monoisotopic mass 333.1320
EC50 :
0.00 µM


Bibliographic data:
Authors
Deng G., Liu Z., Ye F., Luo X., Zhu W., Shen X., Liu H., Jiang H.
Title
Tryptophan-containing dipeptide derivatives as potent PPARγ antagonists: Design, synthesis, biological evaluation, and molecular modeling. Eur. J. Med. Chem., 43, 2699-2716, 2008
Year Source
2008 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@]([H])(CCC(=O)O)C(=O)O

InChI=1S/C16H19N3O5/c17-11(7-9-8-18-12-4-2-1-3-10(9)12)15(22)19-13(16(23)24)5-6-14(20)21/h1-4,8,11,13,18H,5-7,17H2,(H,19,22)(H,20,21)(H,23,24)/t11-,13-/m1/s1

InChIKey=PWIQCLSQVQBOQV-DGCLKSJQSA-N


Database reference:
ChEBI: ID 74868

ChEMBL: ID CHEMBL476172

ChemSpider: ID 24697297

PubChem: CID 25185697