BIOPEP-UWM: Report

ID 11219
Name Thermolysin inhibitor
sequence
{H3PO4}IA
Function:
Inhibitor of thermolysin (EC 3.4.24.27) (MEROPS ID: M04.001)
 
Number of residues
3
Activity code
therm
Activity :
thermolysin inhibitor
Chemical mass 282.2300 Monoisotopic mass 282.0976
IC50 :
0.00 µM


Bibliographic data:
Authors
Kam C. M., Nishino N., Powers J. C.
Title
Inhibition of thermolysin and carboxypeptidase A by phosphoramidates. Biochemistry, 18, 3032-3038, 1979
Year Source
1979 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: OP(=O)(O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C)C(=O)O

InChI=1S/C9H19N2O6P/c1-4-5(2)7(11-18(15,16)17)8(12)10-6(3)9(13)14/h5-7H,4H2,1-3H3,(H,10,12)(H,13,14)(H3,11,15,16,17)/t5-,6-,7-/m0/s1

InChIKey=BIOSNRSPRYKFCL-ACZMJKKPSA-N


{H3PO4} - Phosphoric acid (ID 248 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BindingDB: ID 50474132

ChEMBL: ID CHEMBL2372512

ChemSpider: ID 30809745

PubChem: CID 71355522