BIOPEP-UWM: Report

ID 11223
Name ACE inhibitor
sequence
GPFPILV
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
7
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 741.9148 Monoisotopic mass 741.4411
IC50 :
424.00 µM


Bibliographic data:
Authors
Quirós A., Hernández-Ledesma B., Ramos M., Amigo L., Recio I.
Title
Angiotensin-converting enzyme inhibitory activity of peptides derived from caprine kefir. J. Dairy Sci., 88, 3480-3487, 2005
Year Source
2005 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N1[C@H](C(=O)N[C@H](C(=O)N2[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)O)C(C)C)CC(C)C)[C@H](CC)C)CCC2)Cc2ccccc2)CCC1

InChI=1S/C38H59N7O8/c1-7-24(6)32(36(50)40-26(19-22(2)3)33(47)42-31(23(4)5)38(52)53)43-35(49)29-16-12-18-45(29)37(51)27(20-25-13-9-8-10-14-25)41-34(48)28-15-11-17-44(28)30(46)21-39/h8-10,13-14,22-24,26-29,31-32H,7,11-12,15-21,39H2,1-6H3,(H,40,50)(H,41,48)(H,42,47)(H,43,49)(H,52,53)/t24-,26-,27-,28-,29-,31-,32-/m0/s1

InChIKey=DASCHEQGEKYNTI-YUQDWORRSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 9128); the DFBP database; the EROP-Moscow database; the MBPDB database


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 9128

DFBP: ID DFBPACEI1451; DFBPDPIV0104; DFBPMUFU0388

EROP-Moscow: ID E14701

J-GLOBAL: ID 200907076066123363

MBPDB: Peptide GPFPILV

Nikkaji: ID J2.243.265F

Peptipedia: ID 9696

PubChem: CID 101776033

SureChEMBL: ID SCHEMBL30781626