BIOPEP-UWM: Report

ID 11265
Name Inhibitor of peptidylprolyl isomerase
sequence
<C3:0[3COOH]>AAP~
Function:
Inhibitor of peptidylprolyl isomerase (EC 5.2.1.8)
 
Number of residues
4
Activity code
ppi
Activity :
peptidylprolyl isomerase inhibitor
Chemical mass 356.3733 Monoisotopic mass 356.1690
IC50 :
14000.00 µM


Bibliographic data:
Authors
Demange L., Moutiez M., Vaudry K., Dugave C.
Title
Interaction of human cyclophilin hCyp-18 with short peptides suggests the existence of two functionally independent subsites. FEBS Lett., 505, 191-195, 2001
Year Source
2001 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: OC(=O)CCC(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N

InChI=1S/C15H24N4O6/c1-8(17-11(20)5-6-12(21)22)14(24)18-9(2)15(25)19-7-3-4-10(19)13(16)23/h8-10H,3-7H2,1-2H3,(H2,16,23)(H,17,20)(H,18,24)(H,21,22)/t8-,9-,10-/m0/s1

InChIKey=NMVJYKRWPMUPJD-GUBZILKMSA-N


<C3:0[3COOH]> - Succinic acid - N-terminal modification (ID 257 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BRENDA: Ligand succinyl-Ala-Ala-Pro-NH2