BIOPEP-UWM: Report

ID 11275
Name Inhibitor of peptidylprolyl isomerase
sequence
<s[3*]>P

Function:
Inhibitor of peptidylprolyl isomerase (EC 5.2.1.8)
 
Number of residues
2
Activity code
ppi
Activity :
peptidylprolyl isomerase inhibitor
Chemical mass 282.1871 Monoisotopic mass 282.0613
IC50 :
1000.00 µM



Bibliographic data:
Authors
Zhang Y., Fuessel S., Reimer U., Schutkowski M., Fischer G.
Title
Substrate-based design of reversible Pin1 inhibitors. Biochemistry, 41, 11868-11877, 2002
Year Source
2002 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](COP(=O)(O)O)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C8H15N2O7P/c9-5(4-17-18(14,15)16)7(11)10-3-1-2-6(10)8(12)13/h5-6H,1-4,9H2,(H,12,13)(H2,14,15,16)/t5-,6+/m1/s1

InChIKey=BUFZSKJMMURVEP-RITPCOANSA-N


<s[3*]> - Phospho-D-serine (ID 262 in the BIOPEP-UWM repository of amino acids and modifications)



Database reference:
BRENDA: Ligand D-Ser(PO3H2)-Pro