BIOPEP-UWM: Report

ID 11278
Name Inhibitor of peptidylprolyl isomerase
sequence
<S[3*]>P
Function:
Inhibitor of peptidylprolyl isomerase (EC 5.2.1.8)
 
Number of residues
2
Activity code
ppi
Activity :
peptidylprolyl isomerase inhibitor
Chemical mass 282.1871 Monoisotopic mass 282.0613
IC50 :
2000.00 µM


Bibliographic data:
Authors
Zhang Y., Fuessel S., Reimer U., Schutkowski M., Fischer G.
Title
Substrate-based design of reversible Pin1 inhibitors. Biochemistry, 41, 11868-11877, 2002
Year Source
2002 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](COP(=O)(O)O)C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C8H15N2O7P/c9-5(4-17-18(14,15)16)7(11)10-3-1-2-6(10)8(12)13/h5-6H,1-4,9H2,(H,12,13)(H2,14,15,16)/t5-,6-/m0/s1

InChIKey=BUFZSKJMMURVEP-WDSKDSINSA-N


<S[3*]> - Phosphoserine (ID 108 in the BIOPEP-UWM repository of amino acids and modifications)


Database reference:
BRENDA: Ligand Ser(PO3H2)-Pro