BIOPEP-UWM: Report

ID 11287
Name Tyrosinase inhibitor
sequence
GAPGGAGGVGEPGR
Function:
Inhibitor of Tyrosinase (EC 1.14.18.1)
 
Number of residues
14
Activity code
tyr
Activity :
tyrosinase inhibitor
Chemical mass 1138.1884 Monoisotopic mass 1137.5510
EC50 :
0.00 µM


Bibliographic data:
Authors
Zhang R., Li Y., Li Y., Zhang H.
Title
Discovering potential anti‑skin‑aging peptides in collagen: computer‑assisted rapid screening and structure–activity relationships. Collagen and Leather, 7, 30, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCC(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(C)C(=O)NCC(=O)NCC(=O)N[C@@]([H])(C(C)C)C(=O)NCC(=O)N[C@@]([H])(CCC(=O)O)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O

InChI=1S/C46H75N17O17/c1-23(2)38(42(76)56-22-34(68)59-26(11-12-37(71)72)44(78)63-15-7-10-29(63)41(75)55-21-35(69)60-27(45(79)80)8-5-13-50-46(48)49)61-36(70)20-52-31(65)17-53-39(73)24(3)57-33(67)19-51-32(66)18-54-40(74)28-9-6-14-62(28)43(77)25(4)58-30(64)16-47/h23-29,38H,5-22,47H2,1-4H3,(H,51,66)(H,52,65)(H,53,73)(H,54,74)(H,55,75)(H,56,76)(H,57,67)(H,58,64)(H,59,68)(H,60,69)(H,61,70)(H,71,72)(H,79,80)(H4,48,49,50)/t24-,25-,26-,27-,28-,29-,38-/m0/s1

InChIKey=QVQVSZRJKCDVKX-KWAIQXEUSA-N


Inhibitor of Microbial collagenase (EC 3.4.24.3; MEROPS ID: M09.002) according to the BIOPEP-UWM database of bioactive peptides


Database reference: