BIOPEP-UWM: Report

ID 11308
Name Stimulator of insulin secretion
sequence
LPIA
Function:
Stimulating insulin secretion in cell culture
 
Number of residues
5
Activity code
sins
Activity :
stimulating insulin secretion
Chemical mass 412.5222 Monoisotopic mass 412.2677
EC50 :
0.00 µM


Bibliographic data:
Authors
Cermeño M., Santos-Hernández M., FitzGerald R. J.
Title
Peptides IPVP and LPIA induce insulin secretion in a 2-tiered Caco-2-STC-1/BRIN-BD11 cell model. J. Agric. Food Chem. 2025, 73, 24769–24778, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C)C(=O)O

InChI=1S/C20H36N4O5/c1-6-12(4)16(18(26)22-13(5)20(28)29)23-17(25)15-8-7-9-24(15)19(27)14(21)10-11(2)3/h11-16H,6-10,21H2,1-5H3,(H,22,26)(H,23,25)(H,28,29)/t12-,13-,14-,15-,16-/m0/s1

InChIKey= ZWHYWFPPFJBCQH-QXKUPLGCSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 10327)


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 10327