BIOPEP-UWM: Report

ID 11314
Name ACE inhibitor
sequence
ITH

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 369.4150 Monoisotopic mass 369.2006
IC50 :
28.77 µM



Bibliographic data:
Authors
Gu J., Yue S., Yang X., Lu Z., Wang Z., Wei X., Zhou L., Zhao Z., Shi Z., Zhao Z.
Title
Unlocking novel angiotensin-converting enzyme inhibitory peptides from Nili Ravi buffalo milk β-casein: A synergistic strategy combining targeted hydrolysis, 3D-QSAR modeling, and mechanistic insights. Food Biosci., 71, 107346, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)O

InChI=1S/C16H27N5O5/c1-4-8(2)12(17)14(23)21-13(9(3)22)15(24)20-11(16(25)26)5-10-6-18-7-19-10/h6-9,11-13,22H,4-5,17H2,1-3H3,(H,18,19)(H,20,24)(H,21,23)(H,25,26)/t8-,9+,11-,12-,13-/m0/s1

InChIKey=GMUYXHHJAGQHGB-TUBUOCAGSA-N



Database reference:
ChEBI: ID 158784

EPA CompTox: ID DTXSID70776104

Metabolomics Workbench: ID 82984

PubChem: CID 145456280

UniChem: ID 176704823

Wikidata: ID Q106012363