BIOPEP-UWM: Report

ID 11318
Name ACE inhibitor
sequence
SI

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
2
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 218.2495 Monoisotopic mass 218.1262
IC50 :
188.30 µM



Bibliographic data:
Authors
Gu J., Yue S., Yang X., Lu Z., Wang Z., Wei X., Zhou L., Zhao Z., Shi Z., Zhao Z.
Title
Unlocking novel angiotensin-converting enzyme inhibitory peptides from Nili Ravi buffalo milk β-casein: A synergistic strategy combining targeted hydrolysis, 3D-QSAR modeling, and mechanistic insights. Food Biosci., 71, 107346, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(CO)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)O

InChI=1S/C9H18N2O4/c1-3-5(2)7(9(14)15)11-8(13)6(10)4-12/h5-7,12H,3-4,10H2,1-2H3,(H,11,13)(H,14,15)/t5-,6-,7-/m0/s1

InChIKey=BXLYSRPHVMCOPS-ACZMJKKPSA-N


Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003) according to the BIOPEP-UWM database of bioactive peptides (ID 8893)



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8893

CAS: Registry No 91086-51-0

ChEBI: ID 90326

ChemSpider: ID 57527499

EPA CompTox: ID DTXSID40847714

FooDB: ID FDB112050

HMDB: ID HMDB0029042

Metabolomics Workbench: ID 78965

PubChem: CID 71429009

SureChEMBL: ID 3783793

UniChem: ID 61995522

Wikidata: ID Q27162464