BIOPEP-UWM: Report

ID 11319
Name ACE inhibitor
sequence
PPF

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 359.4185 Monoisotopic mass 359.1839
IC50 :
239.33 µM



Bibliographic data:
Authors
Gu J., Yue S., Yang X., Lu Z., Wang Z., Wei X., Zhou L., Zhao Z., Shi Z., Zhao Z.
Title
Unlocking novel angiotensin-converting enzyme inhibitory peptides from Nili Ravi buffalo milk β-casein: A synergistic strategy combining targeted hydrolysis, 3D-QSAR modeling, and mechanistic insights. Food Biosci., 71, 107346, 2025
Year Source
2025 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

BIOPEP-UWM database of sensory peptides and amino acids


SMILES: N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)O

InChI=1S/C19H25N3O4/c23-17(21-15(19(25)26)12-13-6-2-1-3-7-13)16-9-5-11-22(16)18(24)14-8-4-10-20-14/h1-3,6-7,14-16,20H,4-5,8-12H2,(H,21,23)(H,25,26)/t14-,15-,16-/m0/s1

InChIKey=NAIPAPCKKRCMBL-JYJNAYRXSA-N


Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 59)



Database reference:
BIOPEP-UWM database of sensory peptides and amino acids: ID 59

ChEBI: ID 162604

ChemSpider: ID 8308601

DFBP: ID DFBPACEI2317; DFBPACEI2446

J-GLOBAL: ID 200907063158029644

Metabolomics Workbench: ID 84949

Nikkaji: ID J1.735.080C

PubChem: CID 10133086

SATPdb: ID satpdb14566

SureChEMBL: ID SCHEMBL29484185

UniChem: ID 34695967

Wikidata: ID Q106028093