BIOPEP-UWM: Report

ID 11324
Name Antidiabetic peptide
sequence
CARIY

Function:
Lowering glucose content in blood in mice
 
Number of residues
5
Activity code
adb
Activity :
antidiabetic
Chemical mass 624.7520 Monoisotopic mass 624.3044
IC50 :
0.00 µM



Bibliographic data:
Authors
Li Y., Zhao W., Dong L., Xiang K., Ma J., Cong H., Yu B.
Title
Synthetic α-glucosidase inhibitory peptides designed by molecular docking: In vitro screening and anti-hyperglycemic efficacy in diabetic mice. Eur. J. Med. Chem., 302, 118378, 2026
Year Source
2026 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CS)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C27H44N8O7S/c1-4-14(2)21(25(40)34-20(26(41)42)12-16-7-9-17(36)10-8-16)35-24(39)19(6-5-11-31-27(29)30)33-22(37)15(3)32-23(38)18(28)13-43/h7-10,14-15,18-21,36,43H,4-6,11-13,28H2,1-3H3,(H,32,38)(H,33,37)(H,34,40)(H,35,39)(H,41,42)(H4,29,30,31)/t14-,15-,18-,19-,20-,21-/m0/s1

InChIKey=NIWGFEUDLZSLIZ-XRYUJSLGSA-N


Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides



Database reference: