BIOPEP-UWM: Report

ID 11325
Name Antidiabetic peptide
sequence
CARWY

Function:
Lowering glucose content in blood in mice
 
Number of residues
5
Activity code
adb
Activity :
antidiabetic
Chemical mass 697.8043 Monoisotopic mass 697.2997
IC50 :
0.00 µM



Bibliographic data:
Authors
Li Y., Zhao W., Dong L., Xiang K., Ma J., Cong H., Yu B.
Title
Synthetic α-glucosidase inhibitory peptides designed by molecular docking: In vitro screening and anti-hyperglycemic efficacy in diabetic mice. Eur. J. Med. Chem., 302, 118378, 2026
Year Source
2026 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CS)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)O

InChI=1S/C32H43N9O7S/c1-17(38-28(44)22(33)16-49)27(43)39-24(7-4-12-36-32(34)35)29(45)40-25(14-19-15-37-23-6-3-2-5-21(19)23)30(46)41-26(31(47)48)13-18-8-10-20(42)11-9-18/h2-3,5-6,8-11,15,17,22,24-26,37,42,49H,4,7,12-14,16,33H2,1H3,(H,38,44)(H,39,43)(H,40,45)(H,41,46)(H,47,48)(H4,34,35,36)/t17-,22-,24-,25-,26-/m0/s1

InChIKey=QEMXNZDRSFFPAK-KQUHQIRHSA-N


Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides



Database reference: