BIOPEP-UWM: Report

ID 11430
Name Neuroprotective peptide
sequence
VPRKL{SeM}

Function:
Peptide preventing neurodegeneration in Caenorhabditis elegans
 
Number of residues
6
Activity code
neup
Activity :
neuroprotective
Chemical mass 789.8651 Monoisotopic mass 790.3954
EC50 :
0.00 µM



Bibliographic data:
Authors
Chen M., Zhu Z., Wu S., Huang A., Xie Z., Cai J., Huang R., Yu S., Liu M., Zhang J., Tse Y., Wu Q., Wang J., Ding Y.
Title
SKN-1 is indispensable for protection against Aβ-induced proteotoxicity by a selenopeptide derived from Cordyceps militaris. Redox Biol., 70, 103065, 2024
Year Source
2024 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC[Se]C)C(=O)O

InChI=1S/C33H62N10O7Se/c1-19(2)18-24(29(46)41-23(32(49)50)13-17-51-5)42-28(45)21(10-6-7-14-34)39-27(44)22(11-8-15-38-33(36)37)40-30(47)25-12-9-16-43(25)31(48)26(35)20(3)4/h19-26H,6-18,34-35H2,1-5H3,(H,39,44)(H,40,47)(H,41,46)(H,42,45)(H,49,50)(H4,36,37,38)/t21-,22-,23-,24-,25-,26-/m0/s1

InChIKey=WPRXWXYUQHPURB-FRSCJGFNSA-N

{SeM} - Selenomethionine; ID 128 in the BIOPEP-UWM repository of amino acids and modifications



Database reference: