BIOPEP-UWM: Report

ID 11503
Name Alpha-glucosidase inhibitor
sequence
YPFP

Function:
Inhibitor of alpha-glucosidase (EC 3.2.1.20)
 
Number of residues
4
Activity code
glui
Activity :
alpha-glucosidase inhibitor
Chemical mass 522.5914 Monoisotopic mass 522.2470
IC50 :
0.00 µM



Bibliographic data:
Authors
Cao R., Li W., Zhang J., Bao X., Feng H., Sun J., Liu X., Sun L.
Title
Milk casein hydrolysate peptides regulate starch digestion through inhibition of α-glucosidase: An insight into the active oligopeptide screening, enzyme inhibition behaviors, and oligopeptide-enzyme binding interactions. Food Hydrocolloids, 152, 109926, 2024
Year Source
2024 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@H](CC1=CC=C(C=C1)O)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@H](CC1=CC=C(C=C1))C(=O)N1[C@@]([H])(CCC1)C(=O)O

InChI=1S/C28H34N4O6/c29-21(16-19-10-12-20(33)13-11-19)26(35)31-14-4-8-23(31)25(34)30-22(17-18-6-2-1-3-7-18)27(36)32-15-5-9-24(32)28(37)38/h1-3,6-7,10-13,21-24,33H,4-5,8-9,14-17,29H2,(H,30,34)(H,37,38)/t21-,22-,23-,24-/m0/s1

InChIKey=DCGNJQAPLOBXDM-ZJZGAYNASA-N

Opioid peptide according to the BIOPEP-UWM database of bioactive peptides (ID 2868), the DFBP database, the MBPDB database; the PubChem database



Database reference:
BIOPEP-UWM database of bioactive peptides: ID 2868

BRENDA: Ligand Tyr-Pro-Phe-Pro

CAS: Registry No 74171-19-0

ChemIDplus: ID 074171190

ChemSpider: ID 151269

DFBP: ID DFBPOPIO0044

EPA CompTox: ID DTXSID70225142

EPA DSSTox: ID DTXCID70147633

EROP-Moscow: ID E00536

J-GLOBAL: ID 200907045577749233

MBPDB: Peptide YPFP

MeSH: Terms beta-casomorphin 4; Tyr-pro-Phe-Pro; tyrosyl-prolyl-phenylalanyl-proline

Nikkaji: ID J39.394K

PubChem: CID 173253

SureChEMBL: ID 29368129

UniChem: ID 32044412

Wikidata: ID Q83104066

ZINC: ID ZINC85591238