BIOPEP-UWM: Report

ID 11515
Name Alpha-amylase inhibitor
sequence
RWW
Function:
Inhibitor of Alpha-amylase (EC 3.2.1.1)
 
Number of residues
3
Activity code
aami
Activity :
alpha-amylase inhibitor
Chemical mass 546.6194 Monoisotopic mass 546.2696
IC50 :
0.00 µM


Bibliographic data:
Authors
Khan M., Khan S., Ahmad S., Alshammary F. L., Mahmood T., Khan M. S., Rahim M.
Title
Designed and synthesized novel tripeptides targeting diabetes and its related pathologies. Eur. J. Med. Chem., 283, 117134, 2025
Year Source
2025 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)N[C@@H](CC1=C[NH]C2=CC=CC=C12)C(=O)O

InChI=1S/C28H34N8O4/c29-20(8-5-11-32-28(30)31)25(37)35-23(12-16-14-33-21-9-3-1-6-18(16)21)26(38)36-24(27(39)40)13-17-15-34-22-10-4-2-7-19(17)22/h1-4,6-7,9-10,14-15,20,23-24,33-34H,5,8,11-13,29H2,(H,35,37)(H,36,38)(H,39,40)(H4,30,31,32)/t20-,23-,24-/m0/s1

InChIKey=WAEWODAAWLGLMK-OYDLWJJNSA-N


Antioxidative peptide according to the BIOPEP-UWM database of bioactive peptides (ID 8080)
Glycation suppressing peptide according to the BIOPEP-UWM database of bioactive peptides; the ChEMBL database
Inhibitor of Alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides; the ChEMBL database


Database reference:
BIOPEP-UWM database of bioactive peptides: ID 8080

ChEBI: ID 159390

ChEMBL: ID CHEMBL6171834

Metabolomics Workbench: ID 79813

PubChem: CID 145453971

SureChEMBL: ID 30671629

UniChem: ID 176702547

Wikidata: ID Q106013099