BIOPEP-UWM: Report

ID 11557
Name Homocarnosine – carnosinase inhibitor
sequence
{GABA}H
Function:
Inhibitor of carnosinase (EC 3.4.13.20; MEROPS ID M20.006)
 
Number of residues
2
Activity code
carn
Activity :
carnosinase inhibitor
Chemical mass 240.2584 Monoisotopic mass 240.1219
IC50 :
0.00 µM


Bibliographic data:
Authors
Peters V., Kebbewar M., Jansen E. W., Jakobs C., Riedl E., Koeppel H., Frey D., Adelmann K., Klingbeil K., Mack M., Hoffmann G. F., Janssen B., Zschocke J., Yard B. A.
Title
Relevance of allosteric conformations and homocarnosine concentration on carnosinase activity. Amino Acids, 38, 1607-1615, 2010
Year Source
2010 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: NCCCC(=O)N[C@@H](CC1=CN=C[NH]1)C(=O)O

InChI=1S/C10H16N4O3/c11-3-1-2-9(15)14-8(10(16)17)4-7-5-12-6-13-7/h5-6,8H,1-4,11H2,(H,12,13)(H,14,15)(H,16,17)/t8-/m0/s1

InChIKey=CCLQKVKJOGVQLU-QMMMGPOBSA-N


{GABA} – γ-Aminobutyric acid; ID 196 in the BIOPEP-UWM repository of amino acids and modifications


Antioxidative peptide according to the ChEMBL database
Copper-binding peptide according to the ChEMBL database


Database reference:
BioCyc: ID CPD-12185

Bovine Metabolome Database: ID BMDB0000745

BRENDA: Ligand homocarnosine

CAS: Registry No 3650-73-5

ChEBI: ID 85981

ChEMBL: ID CHEMBL243618

Chemspider: ID 8418848

CSF Metabolome database: ID HMDB0000745

ECMDB: ID ECMDB00745

EPA DSSTox: ID DTXSID001351383

FooDB: ID FDB022217

HMDB: ID HMDB0000745

KEGG: ID C00884

MassBank: ID KO000978_eu

MeSH: terms homocarnosine; gamma-aminobutyryl-L-histidine

MetaboLights: ID MTBLC85981

Metabolomics Workbench: ID 37403

Nikkaji: ID J14.557B

PubChem: CID 10243361

SMPDB: ID PW_C000593

SureChEMBL: ID SCHEMBL541262

UniChem: ID 404236

UNII: ID M8L4BH36SC

VMH: ID HC00576

Wikidata: ID Q27158831