BIOPEP-UWM: Report

ID 11612
Name ACE inhibitor
sequence
LEIVPK

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 697.8607 Monoisotopic mass 697.4360
IC50 :
1275.00 µM



Bibliographic data:
Authors
Gómez Ruiz J. Á., Ramos M., Recio I.
Title
Angiotensin converting enzyme-inhibitory activity of peptides isolated from Manchego cheese. Stability under simulated gastrointestinal digestion. Int. Dairy J., 14, 1075-1080, 2004
Year Source
2004 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)O

InChI=1S/C33H59N7O9/c1-7-20(6)27(39-29(44)22(13-14-25(41)42)36-28(43)21(35)17-18(2)3)31(46)38-26(19(4)5)32(47)40-16-10-12-24(40)30(45)37-23(33(48)49)11-8-9-15-34/h18-24,26-27H,7-17,34-35H2,1-6H3,(H,36,43)(H,37,45)(H,38,46)(H,39,44)(H,41,42)(H,48,49)/t20-,21-,22-,23-,24-,26-,27-/m0/s1

InChIKey=FMGKUDFGYOKBMZ-RNIUOSIHSA-N



Database reference: