BIOPEP-UWM: Report
| ID | 11614 |
| Name | Hypotensive peptide |
| sequence |
| Function: | |||
| Lowering blood pressure in rats | |||
| Number of residues | 3 |
Activity code | hyp |
| Activity : | hypotensive |
|||
| Chemical mass | 325.4022 | Monoisotopic mass | 325.1995 | |
| EC50 : | 0.00 µM |
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| Bibliographic data: | |
| Authors | |
| Chen C.-C., Hou Y.-J., Lo H.-Y., Stevens M.-L., Hsiang C.-Y., Ho T.-Y. | |
| Title | |
| Integrated abundance analysis and artificial intelligence-assisted screening reveal novel antihypertensive milk-derived tripeptides. Food Chem., 530, 151275, 2026 | |
| Year | Source |
| 2026 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](C)(CC)[C@]([H])(N)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C16H27N3O4/c1-3-10(2)13(17)15(21)18-8-4-6-11(18)14(20)19-9-5-7-12(19)16(22)23/h10-13H,3-9,17H2,1-2H3,(H,22,23)/t10-,11-,12-,13-/m0/s1 InChIKey=FQYQMFCIJNWDQZ-CYDGBPFRSA-N Review concerning the peptide: Li S., Bu T., Zheng J., Liu L., He G., Wu J., 2019, Preparation, bioavailability, and mechanism of emerging activities of Ile-Pro-Pro and Val-Pro-Pro. Compr. Rev. Food Sci. Food Saf., 18, 1097-1110 Antiinflammatory peptide according to the MBPDB database; the BIOPEP-UWM database of bioactive peptides (ID 9537) Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) according to the BIOPEP-UWM database of bioactive peptides (ID 3522) Inhibitor of alpha-amylase (EC 3.2.1.1) according to the BIOPEP-UWM database of bioactive peptides (ID 10286) Inhibitor of alpha-glucosidase (EC 3.2.1.20) according to the BIOPEP-UWM database of bioactive peptides (ID 10311) Inhibitor of the Angiotensin 2-converting enzyme (EC 3.4.17.23) (MEROPS ID: M02.006) according tp the BIOPEP-UWM database of bioactive peptides (ID 10632) |
| Database reference: |
| AHTPDB: ID 1147, 1276, 1545, 1625, 1672, 1710, 2008, 2243, 2741, 2970, 3402, 3629, 3732, 3775, 3954, 4081, 4177, 4750, 4965, 4966, 5126, 5219, 5514, 5573, 6046, 6093, 6440 BindingDB: ID 50169149 BioPepDB: ID biopep00562 BIOPEP-UWM database of bioactive peptides: ID 3522, 9537, 10286, 10311, 10632 BRENDA: Ligand Ile-Pro-Pro CAS: Registry No 26001-32-1 ChEBI: ID 158716 ChEMBL: ID CHEMBL190994 ChemIDplus: ID 26001-32-1 ChemSpider: ID 8124823 CTD: ID 26001-32-1 DFBP: ID DFBPACEI0294; DFBPACEI0341, DFBPANHY0110, DFBPANHY0876, DFBPMUFU0089 DSLD: compound Isoleucyl-prolyl-proline Drug Information Portal: ID 26001-32-1 eChemPortal: ID 26001-32-1 EROP-Moscow: ID E07047 J-GLOBAL: ID 200907029257440891 MBPDB: Peptide IPP MeSH: Terms isoleucyl-prolyl-proline, Ile-Pro-Pro, IPP peptide, isoleucine-proline-proline Metabolomics Workbench: ID 82950 Nikkaji: ID J667.339B Probes And Drugs: ID PD102229 PubChem: CID 9949212 SATPdb: ID satpdb14611 SureChEMBL: ID SCHEMBL1646849 UniChem: ID 198678 Wikidata: ID Q106026895 ZINC: ID ZINC000013646353 |