BIOPEP-UWM: Report

ID 2582
Name tenecin-1 (34-43)
sequence
CNGKRVCVCR~
Function:
Antimicrobial peptide
 
Number of residues
10
Activity code
ab
Activity :
antibacterial
Chemical mass 1136.4190 Monoisotopic mass 1135.5509
EC50 :
0.00 µM


Bibliographic data:
Authors
Lee K. H., Hong Y. S., Oh J. E., Kwon M., Yoon J. H., Lee J., Lee B. L., Moon H. M.
Title
Identification and characterization of the antimicrobial peptide corresponding to C-terminal beta-sheet domain of tenecin 1, an antibacterial protein of larvae of Tenebrio molitor. Biochem. J., 334, 99-105 (1998).
Year Source
1998 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@](C(N[C@](C(NCC(N[C@](C(N[C@](C(N[C@](C(N[C@](C(N[C@](C(N[C@](C(N[C@](C(N)=O)(CCCNC(N)=N)[H])=O)(CS)[H])=O)(C(C)C)[H])=O)(CS)[H])=O)(C(C)C)[H])=O)(CCCNC(N)=N)[H])=O)(CCCCN)[H])=O)=O)(CC(N)=O)[H])=O)(CS)[H]

InChI=1S/C43H81N19O11S3/c1-20(2)31(40(72)60-28(19-76)39(71)62-32(21(3)4)41(73)59-27(18-75)38(70)56-23(33(47)65)10-7-13-52-42(48)49)61-37(69)25(11-8-14-53-43(50)51)57-36(68)24(9-5-6-12-44)55-30(64)16-54-35(67)26(15-29(46)63)58-34(66)22(45)17-74/h20-28,31-32,74-76H,5-19,44-45H2,1-4H3,(H2,46,63)(H2,47,65)(H,54,67)(H,55,64)(H,56,70)(H,57,68)(H,58,66)(H,59,73)(H,60,72)(H,61,69)(H,62,71)(H4,48,49,52)(H4,50,51,53)/t22-,23-,24-,25-,26-,27-,28-,31-,32-/m0/s1

InChIKey: MJTUKAGRPPTOTE-NQTAILCISA-N


This fragment shows activity against fungi and G(+) bacteria. The active form of this fragment contains C-terminal amide.


Database reference: