BIOPEP-UWM: Report

ID 2586
Name tenecin-1 (33-43)
sequence
YCNGKRVCVCR~

Function:
Antibacterial peptide
 
Number of residues
11
Activity code
ab
Activity :
antibacterial
Chemical mass 1299.5919 Monoisotopic mass 1298.6140
EC50 :
0.00 µM



Bibliographic data:
Authors
Lee K. H., Hong Y. S., Oh J. E., Kwon M., Yoon J. H., Lee J., Lee B. L., Moon H. M.
Title
Identification and characterization of the antimicrobial peptide corresponding to C-terminal beta-sheet domain of tenecin 1, an antibacterial protein of larvae of Tenebrio molitor. Biochem. J., 334, 99-105 (1998).
Year Source
1998 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)NCC(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N[C@H](C(=O)N)CCCNC(=N)N)CS)C(C)C)CS)C(C)C)CCCNC(=N)N)CCCCN)CC(=O)N)CS)Cc1ccc(O)cc1

InChI=1S/C52H90N20O13S3/c1-25(2)39(49(84)70-36(24-88)48(83)72-40(26(3)4)50(85)69-35(23-87)46(81)65-30(41(56)76)10-7-17-61-51(57)58)71-45(80)32(11-8-18-62-52(59)60)66-44(79)31(9-5-6-16-53)64-38(75)21-63-43(78)33(20-37(55)74)67-47(82)34(22-86)68-42(77)29(54)19-27-12-14-28(73)15-13-27/h12-15,25-26,29-36,39-40,73,86-88H,5-11,16-24,53-54H2,1-4H3,(H2,55,74)(H2,56,76)(H,63,78)(H,64,75)(H,65,81)(H,66,79)(H,67,82)(H,68,77)(H,69,85)(H,70,84)(H,71,80)(H,72,83)(H4,57,58,61)(H4,59,60,62)/t29-,30-,31-,32-,33-,34-,35-,36-,39-,40-/m0/s1

InChIKey: XQVBLENYHQYYRF-ZRUUCOTKSA-N


This fragment shows activity against fungi and G(+) bacteria. The active form of this fragment is C-terminal amide.



Database reference: