BIOPEP-UWM: Report

ID 2606
Name PEP inhibitor
sequence
HLPLPL

Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
6
Activity code
am
Activity :
antiamnestic
Chemical mass 688.8556 Monoisotopic mass 688.4259
EC50 :
10.00 µM



Bibliographic data:
Authors
Asano M., Nio N., Ariyoshi Y.
Title
Inhibition of prolyl endopeptidase by synthetic beta-casein peptides and their derivatives with a C-terminal prolinol or prolinal. Biosci. Biotech. Biochem., 56, 976-977 (1992)
Year Source
1992 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(Cc1cnc[nH]1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(C)C)C(O)=O

InChI=1S/C34H56N8O7/c1-19(2)13-24(38-29(43)23(35)16-22-17-36-18-37-22)32(46)41-11-7-9-27(41)30(44)39-25(14-20(3)4)33(47)42-12-8-10-28(42)31(45)40-26(34(48)49)15-21(5)6/h17-21,23-28H,7-16,35H2,1-6H3,(H,36,37)(H,38,43)(H,39,44)(H,40,45)(H,48,49)/t23-,24-,25-,26-,27-,28-/m0/s1

InChIKey=YXQGXTCMTANECD-QUQVWLGBSA-N



Database reference:
EROP-Moscow: ID E14662