BIOPEP-UWM: Report

ID 2607
Name PEP inhibitor
sequence
LYPFVEPI

Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
8
Activity code
am
Activity :
antiamnestic
Chemical mass 977.1502 Monoisotopic mass 976.5252
EC50 :
30.00 µM



Bibliographic data:
Authors
Asano M., Nio N., Ariyoshi Y.
Title
Inhibition of prolyl endopeptidase by synthetic beta-casein peptides and their derivatives with a C-terminal prolinol or prolinal. Biosci. Biotech. Biochem., 56, 976-977 (1992)
Year Source
1992 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(CC(C)C)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(O)=O

InChI=1S/C50H72N8O12/c1-7-30(6)42(50(69)70)56-46(65)39-16-12-23-57(39)48(67)35(21-22-40(60)61)52-47(66)41(29(4)5)55-44(63)36(26-31-13-9-8-10-14-31)53-45(64)38-15-11-24-58(38)49(68)37(27-32-17-19-33(59)20-18-32)54-43(62)34(51)25-28(2)3/h8-10,13-14,17-20,28-30,34-39,41-42,59H,7,11-12,15-16,21-27,51H2,1-6H3,(H,52,66)(H,53,64)(H,54,62)(H,55,63)(H,56,65)(H,60,61)(H,69,70)/t30-,34-,35-,36-,37-,38-,39-,41-,42-/m0/s1


InChIKey: HABAKDPYTFWREO-KDWUJUPASA-N



Database reference: