BIOPEP-UWM: Report

ID 2608
Name PEP inhibitor
sequence
IYPFPGPIP

Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
9
Activity code
am
Activity :
antiamnestic
Chemical mass 1000.1868 Monoisotopic mass 999.5412
EC50 :
50.00 µM



Bibliographic data:
Authors
Asano M., Nio N., Ariyoshi Y.
Title
Inhibition of prolyl endopeptidase by synthetic beta-casein peptides and their derivatives with a C-terminal prolinol or prolinal. Biosci. Biotech. Biochem., 56, 976-977 (1992)
Year Source
1992 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)([C@@H](C)CC)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N1CCC[C@@]1([H])C(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C52H73N9O11/c1-5-31(3)43(53)48(67)56-37(29-34-20-22-35(62)23-21-34)50(69)60-26-12-18-40(60)46(65)55-36(28-33-14-8-7-9-15-33)49(68)59-25-11-16-38(59)45(64)54-30-42(63)58-24-10-17-39(58)47(66)57-44(32(4)6-2)51(70)61-27-13-19-41(61)52(71)72/h7-9,14-15,20-23,31-32,36-41,43-44,62H,5-6,10-13,16-19,24-30,53H2,1-4H3,(H,54,64)(H,55,65)(H,56,67)(H,57,66)(H,71,72)/t31-,32-,36-,37-,38-,39-,40-,41-,43-,44-/m0/s1

InChIKey: GHSJDPBMKTWWBH-MSEMKWBCSA-N



Database reference: