BIOPEP-UWM: Report

ID 2609
Name PEP inhibitor
sequence
IYPVPEPS

Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
8
Activity code
am
Activity :
antiamnestic
Chemical mass 901.0115 Monoisotopic mass 900.4577
EC50 :
280.00 µM



Bibliographic data:
Authors
Asano M., Nio N., Ariyoshi Y.
Title
Inhibition of prolyl endopeptidase by synthetic beta-casein peptides and their derivatives with a C-terminal prolinol or prolinal. Biosci. Biotech. Biochem., 56, 976-977 (1992)
Year Source
1992 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)([C@@H](C)CC)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(C(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CO)C(O)=O

InChI=1S/C43H64N8O13/c1-5-24(4)34(44)39(59)46-28(21-25-12-14-26(53)15-13-25)41(61)50-19-7-11-32(50)38(58)48-35(23(2)3)42(62)51-20-8-10-31(51)36(56)45-27(16-17-33(54)55)40(60)49-18-6-9-30(49)37(57)47-29(22-52)43(63)64/h12-15,23-24,27-32,34-35,52-53H,5-11,16-22,44H2,1-4H3,(H,45,56)(H,46,59)(H,47,57)(H,48,58)(H,54,55)(H,63,64)/t24-,27-,28-,29-,30-,31-,32-,34-,35-/m0/s1

InChIKey: POEQXWBIQPDVRI-UICVVSPGSA-N



Database reference: