BIOPEP-UWM: Report

ID 2616
Name PEP inhibitor
sequence
IFPFVEPI

Function:
Inhibitor of prolyl oligopeptidase (EC 3.4.21.26) (MEROPS ID: S09.001)
 
Number of residues
8
Activity code
am
Activity :
antiamnestic
Chemical mass 961.1508 Monoisotopic mass 960.5303
EC50 :
25.00 µM



Bibliographic data:
Authors
Asano M., Nio N., Ariyoshi Y.
Title
Inhibition of prolyl endopeptidase by synthetic beta-casein peptides and their derivatives with a C-terminal prolinol or prolinal. Biosci. Biotech. Biochem., 56, 976-977 (1992)
Year Source
1992 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)([C@@H](C)CC)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(O)=O

InChI=1S/C50H72N8O11/c1-7-30(5)40(51)46(64)54-36(28-33-19-13-10-14-20-33)49(67)58-26-15-21-37(58)44(62)53-35(27-32-17-11-9-12-18-32)43(61)55-41(29(3)4)47(65)52-34(23-24-39(59)60)48(66)57-25-16-22-38(57)45(63)56-42(50(68)69)31(6)8-2/h9-14,17-20,29-31,34-38,40-42H,7-8,15-16,21-28,51H2,1-6H3,(H,52,65)(H,53,62)(H,54,64)(H,55,61)(H,56,63)(H,59,60)(H,68,69)/t30-,31-,34-,35-,36-,37-,38-,40-,41-,42-/m0/s1

InChIKey: IWDUAPNWNXFCPI-NPFSXUQRSA-N



Database reference: