BIOPEP-UWM: Report

ID 2627
Name ACE inhibitor
sequence
IYP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
3
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 391.4602 Monoisotopic mass 391.2100
EC50 :
61.00 µM



Bibliographic data:
Authors
Kohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y.
Title
Inhibition of angiotensin-converting enzyme by synthetic peptides of human beta-casein. Agric. Biol. Chem., 53(8), 2107-2114 (1989)
Year Source
1989 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)([C@@H](C)CC)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C20H29N3O5/c1-3-12(2)17(21)18(25)22-15(11-13-6-8-14(24)9-7-13)19(26)23-10-4-5-16(23)20(27)28/h6-9,12,15-17,24H,3-5,10-11,21H2,1-2H3,(H,22,25)(H,27,28)/t12-,15-,16-,17-/m0/s1

InChIKey: NSPNUMNLZNOPAQ-STECZYCISA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001



Database reference:
AHTPDB: ID 3663, 3963, 4765, 5224, 5966, 6296, 6783, 6791

ChemSpider: ID 8447249

EROP-Moscow: ID E14582

MBPDB: Peptide IYP

PubChem: CID 10271770

SATPdb: ID satpdb17470