BIOPEP-UWM: Report

ID 2628
Name ACE inhibitor
sequence
LIYP

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
4
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 504.6174 Monoisotopic mass 504.2938
EC50 :
10.00 µM



Bibliographic data:
Authors
Kohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y.
Title
Inhibition of angiotensin-converting enzyme by synthetic peptides of human beta-casein. Agric. Biol. Chem., 53(8), 2107-2114 (1989)
Year Source
1989 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(CC(C)C)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C26H40N4O6/c1-5-16(4)22(29-23(32)19(27)13-15(2)3)24(33)28-20(14-17-8-10-18(31)11-9-17)25(34)30-12-6-7-21(30)26(35)36/h8-11,15-16,19-22,31H,5-7,12-14,27H2,1-4H3,(H,28,33)(H,29,32)(H,35,36)/t16-,19-,20-,21-,22-/m0/s1

InChIKey: YRRQQCVKJULOHR-XSXWSVAESA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001



Database reference:
AHTPDB: ID 3664, 4899, 5287, 5967, 6297, 6784, 6792

EROP-Moscow: ID E14583

MBPDB: Peptide LIYP

SATPdb: ID satpdb15991