BIOPEP-UWM: Report

ID 2630
Name ACE inhibitor
sequence
QPLIYP
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 729.8612 Monoisotopic mass 729.4048
EC50 :
3.60 µM


Bibliographic data:
Authors
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
Title
Inhibition of angiotensin-converting enzyme by synthetic peptides of human beta-casein. Agric. Biol. Chem., 53(8), 2107-2114 (1989)
Year Source
1989 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides

SMILES: [H][C@](N)(CCC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C36H55N7O9/c1-5-21(4)30(33(48)40-26(19-22-10-12-23(44)13-11-22)35(50)43-17-7-9-28(43)36(51)52)41-31(46)25(18-20(2)3)39-32(47)27-8-6-16-42(27)34(49)24(37)14-15-29(38)45/h10-13,20-21,24-28,30,44H,5-9,14-19,37H2,1-4H3,(H2,38,45)(H,39,47)(H,40,48)(H,41,46)(H,51,52)/t21-,24-,25-,26-,27-,28-,30-/m0/s1

InChIKey: UHWSXOYRCJDMLD-YYNHRMGXSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
AHTPDB: ID 5384, 5969, 6299, 6794

EROP-Moscow: ID E14585

MBPDB: Peptide QPLIYP

SATPdb: ID satpdb12485