BIOPEP-UWM: Report
| ID | 2642 |
| Name | ACE inhibitor |
| sequence |
| Function: | |||
| Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001) | |||
| Number of residues | 3 |
Activity code | ah |
| Activity : | ACE inhibitor |
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| Chemical mass | 341.4445 | Monoisotopic mass | 341.2307 | |
| EC50 : | 270.00 µM |
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| Bibliographic data: | |
| Authors | |
| Kohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y. | |
| Title | |
| Inhibition of angiotensin-converting enzyme by synthetic peptides of human beta-casein. Agric. Biol. Chem., 53(8), 2107-2114 (1989) | |
| Year | Source |
| 1989 | Journal |
| Additional information: |
| BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)([C@@H](C)CC)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C17H31N3O4/c1-5-11(4)14(18)15(21)19-12(9-10(2)3)16(22)20-8-6-7-13(20)17(23)24/h10-14H,5-9,18H2,1-4H3,(H,19,21)(H,23,24)/t11-,12-,13-,14-/m0/s1 InChIKey: PMMMQRVUMVURGJ-XUXIUFHCSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001 Peptide found also in amaranth protein hydrolysate. Barba de la Rosa A. P., Barba Montoya A., Martínez-Cuevas P., Hernández-Ledesma B., León-Galván M. F., De León-Rodríguez A., González C., 2010, Tryptic amaranth glutelin digests induce endothelial nitric oxide production through inhibition of ACE: antihypertensive role of amaranth peptides. Nitric Oxide, 23, 106-111 |
| Database reference: |
| AHTPDB: ID 1582, 3193, 3296, 3951, 4080, 4744, 5217, 5595, 5982, 6309, 6807 BindingDB: ID 50049792 ChEMBL: ID CHEMBL3322005 ChemSpider: ID 58109317 EROP-Moscow: ID E14596, E09247 MBPDB: Peptide ILP PubChem: CID 14889702 SATPdb: ID satpdb27751 |