BIOPEP-UWM: Report

ID 2656
Name synthetic fr. of human beta-CN (161-166) ACE inhibitor
sequence
VLPIPQ

Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
6
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 665.8190 Monoisotopic mass 665.4099
EC50 :
5300.00 µM



Bibliographic data:
Authors
Kohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y.
Title
Inhibition of angiotensin-converting enzyme by synthetic peptides of human beta-casein. Agric. Biol. Chem., 53(8), 2107-2114 (1989)
Year Source
1989 Journal



Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@](N)(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(O)=O

InChI=1S/C32H55N7O8/c1-7-19(6)26(31(45)39-15-9-10-22(39)27(41)35-20(32(46)47)12-13-24(33)40)37-28(42)23-11-8-14-38(23)30(44)21(16-17(2)3)36-29(43)25(34)18(4)5/h17-23,25-26H,7-16,34H2,1-6H3,(H2,33,40)(H,35,41)(H,36,43)(H,37,42)(H,46,47)/t19-,20-,21-,22-,23-,25-,26-/m0/s1

InChIKey: JHWMCQQHLVOYEE-DRKCKIEBSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001



Database reference: