BIOPEP-UWM: Report

ID 2661
Name ACE inhibitor
sequence
PQPIP
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
5
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 550.6460 Monoisotopic mass 550.3105
EC50 :
340.00 µM


Bibliographic data:
Authors
Kohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y.
Title
Inhibition of angiotensin-converting enzyme by synthetic peptides of human beta-casein. Agric. Biol. Chem., 53(8), 2107-2114 (1989)
Year Source
1989 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@@](CCC(N)=O)(NC(=O)[C@]1([H])CCCN1)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N1CCC[C@@]1([H])C(O)=O

InChI=1S/C26H42N6O7/c1-3-15(2)21(25(37)32-14-6-9-19(32)26(38)39)30-23(35)18-8-5-13-31(18)24(36)17(10-11-20(27)33)29-22(34)16-7-4-12-28-16/h15-19,21,28H,3-14H2,1-2H3,(H2,27,33)(H,29,34)(H,30,35)(H,38,39)/t15-,16-,17-,18-,19-,21-/m0/s1

InChIKey: MHFRWPJZAGBTQJ-WVBSATCKSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
AHTPDB: ID 2489, 5334, 6007, 6324, 6832

EROP-Moscow: ID E14615

MBPDB: Peptide PQPIP

SATPdb: ID satpdb13790