BIOPEP-UWM: Report

ID 2672
Name ACE inhibitor
sequence
ENLHLPLP
Function:
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
 
Number of residues
8
Activity code
ah
Activity :
ACE inhibitor
Chemical mass 932.0717 Monoisotopic mass 931.5111
EC50 :
155.00 µM


Bibliographic data:
Authors
Kohmura M., Nio N., Kubo K., Minoshima Y., Munekata E., Ariyoshi Y.
Title
Inhibition of angiotensin-converting enzyme by synthetic peptides of human beta-casein. Agric. Biol. Chem., 53(8), 2107-2114 (1989)
Year Source
1989 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [C@H](N)(CCC(O)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=CN=C[N]1[H])C(=O)N[C@@H](CC(C)C)C(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(C)C)C(=O)N3CCC[C@H]3C(O)=O

InChI=1S/C43H69N11O12/c1-22(2)15-27(49-39(61)29(19-34(45)55)48-36(58)26(44)11-12-35(56)57)37(59)50-28(18-25-20-46-21-47-25)38(60)51-30(16-23(3)4)41(63)53-13-7-9-32(53)40(62)52-31(17-24(5)6)42(64)54-14-8-10-33(54)43(65)66/h20-24,26-33H,7-19,44H2,1-6H3,(H2,45,55)(H,46,47)(H,48,58)(H,49,61)(H,50,59)(H,51,60)(H,52,62)(H,56,57)(H,65,66)/t26-,27-,28-,29-,30-,31-,32-,33-/m0/s1

InChIKey: WMYCAJATMIEXMG-DKTXOJPGSA-N


Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/); ID: M02-001


Database reference:
AHTPDB: ID 3459, 6004, 6334, 6829

EROP-Moscow: ID E14612

FeptideDB: ID 2672

MBPDB: Peptide ENLHLPLP

SATPdb: ID satpdb16855