BIOPEP-UWM: Report

ID 2676
Name Erythropoietin mimetic
sequence
GGVYACRMGPITWVCSPLGG
Function:
Stimulates red blood cells creation
 
Number of residues
20
Activity code
sti
Activity :
stimulating
Chemical mass 2024.3872 Monoisotopic mass 2022.9447
EC50 :
0.00 µM


Bibliographic data:
Authors
Wrighton N. C., Farrell F. X., Chang R., Kashyap A. K., Barbone F. P., Mulcahy L. S., Johnson D. L., Barrett R. W., Jolliffe L. K., Dower W. J.
Title
Small peptides as potent mimetics of the protein hormone erythropoietin. Science, 273, 458-463, 1996
Year Source
1996 Journal


Additional information:
BIOPEP-UWM database of bioactive peptides


SMILES: [H][C@@](C)(NC(=O)[C@]([H])(Cc1ccc(O)cc1)NC(=O)[C@@]([H])(NC(=O)CNC(=O)CN)C(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CCCNC(N)=N)C(=O)N[C@@]([H])(CCSC)C(=O)NCC(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])([C@@H](C)O)C(=O)N[C@@]([H])(Cc1c[nH]c2ccccc12)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CS)C(=O)N[C@@]([H])(CO)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CC(C)C)C(=O)NCC(=O)NCC(O)=O

InChI=1S/C89H138N24O24S3/c1-12-47(8)72(86(135)111-73(49(10)115)87(136)104-59(34-51-36-94-54-19-14-13-18-53(51)54)79(128)109-71(46(6)7)85(134)107-62(43-139)81(130)105-60(41-114)88(137)113-30-17-22-64(113)82(131)102-57(32-44(2)3)76(125)97-37-66(118)96-40-69(121)122)110-83(132)63-21-16-29-112(63)68(120)39-98-75(124)56(27-31-140-11)101-77(126)55(20-15-28-93-89(91)92)100-80(129)61(42-138)106-74(123)48(9)99-78(127)58(33-50-23-25-52(116)26-24-50)103-84(133)70(45(4)5)108-67(119)38-95-65(117)35-90/h13-14,18-19,23-26,36,44-49,55-64,70-73,94,114-116,138-139H,12,15-17,20-22,27-35,37-43,90H2,1-11H3,(H,95,117)(H,96,118)(H,97,125)(H,98,124)(H,99,127)(H,100,129)(H,101,126)(H,102,131)(H,103,133)(H,104,136)(H,105,130)(H,106,123)(H,107,134)(H,108,119)(H,109,128)(H,110,132)(H,111,135)(H,121,122)(H4,91,92,93)/t47-,48-,49+,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,70-,71-,72-,73-/m0/s1

InChIKey: YRJBCEXSVRXNKV-HVMLYOJHSA-N


Database reference: